• Novaling@lemmy.zip
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    3 months ago

    Reading this as my body went fucking nuclear on me the moment my allergy meds wore off and I was a fucking tears and snot fountain at 1am until I took a Zyrtec until it chilled by 2. Even then, I still have fucking drop going on in the back of my throat… ugh…

      • Confused_Emus@lemmy.dbzer0.com
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        3 months ago

        That fucking trash. I’ve got vasovagal syncope.

        A sudden drop in heart rate and blood pressure leading to fainting, often in reaction to a stressful trigger.

        Common triggers include strain, stress, long periods of standing, heat exposure, or the sight of blood.

        Symptoms include paleness, nausea, sweating, a rapid heartbeat, and fainting.

        It’s inconsistent, though. For example, never had issues with the numbing shots at the dentist. One day they start giving the shots to numb me up, and next thing I remember they’ve got me sitting up over a trash can trying to clear the vomit I was aspirating on. Scared the shit out of those dentists.

        Once while in middle school I lightly nicked a finger with some scissors - barely even bled. All of a sudden I feel nauseous and ask to go to the bathroom. I manage to get out into the hallway before collapsing to the floor, hitting my head at least twice on the way down and traumatizing my classmates who thought I just dropped dead.

        Intelligent design my big gay ass. Damn vagus nerve is a dodgy self-destruct mechanism.

        • Obinice@lemmy.world
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          3 months ago

          You may be a fainting goat. Have you checked for hooves? That’s a good sign you may be a fainting goat

  • doug@lemmy.today
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    3 months ago

    Anyone have experience with the shots you can get to mitigate allergies/immunotherapy? I was thinking about getting them to temper my chronic sinusitis, and I don’t want to take Claritin for life.

    • K4mpfie@feddit.org
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      3 months ago

      They can be effective. But speak with your doc first. I found them rather tedious as a kid

    • Confused_Emus@lemmy.dbzer0.com
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      3 months ago

      I took them for a few years in middle/high school, and they worked well for me. If you don’t feel like going to a doctor every week for the shots (and you aren’t too freaked out by needles) you can usually also administer them yourself. My roommate in high school hated needles and shots, so I’d of course make sure to administer the shots while he was in the room.

      • doug@lemmy.today
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        3 months ago

        My spouse administers their own shots for their Chron’s disease medication; are the shots pretty much like… the tubular thingies wherein the needle’s kinda hidden and all you feel is the prick after pressing a button? Or is it like… the full-on here’s-a-fucking-needle-good-luck-chump shot?

        • Confused_Emus@lemmy.dbzer0.com
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          3 months ago

          It’s been years since I took them, but at the time I used something that looks like the image below. Not a huge needle, and injected into an area with fatty tissue like the thigh or stomach so didn’t really hurt either.

  • disguy_ovahea@lemmy.world
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    3 months ago

    *Histamines. Antibodies are far less disruptive. Histamines are far larger, originally protecting us from larger invaders like worms and other parasites. Antihistamines antagonize histamines at receptor sites, preventing the itchy, red, swelling reaction we associate with an allergen.

    • yetAnotherUser@discuss.tchncs.de
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      3 months ago

      Are you sure histamines are larger than antibodies?

      That’s 17 atoms if I can count correctly.

      Antibodies are made of proteins and should therefore be much larger.

      • disguy_ovahea@lemmy.world
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        3 months ago

        I just confirmed. They’re only 17 atoms in size. My memory failed me. I edited the comment. Thanks for the correction!

    • K[r]ukenberg@lemmy.world
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      3 months ago

      Acktually – IgE(/antibodies) are bound to the surface of mast cells. Antigens/allergens bind to the IgE receptor and actives the mast cell, releasing histamines. Allergy can actually be treated with anti-IgE (monoclonal) antibodies (Omalizumab)!