

Just for some background information on how most countries tend to rely on larger, more rigorous regulatory bodies…
I am in the pharma industry (not in vaccines though). Typically the two main regulators that most other countries look to as a reference are either the FDA or the EMA (the EU organization). This usually means that if you can satisfy the requirements of one of these bodies, then it is satisfactory for the other country as well. However, it isn’t universal as each other country will usually have some modifications here and there for whatever reason. The most annoyingly particular ones I have dealt with in the past are China and Japan.
I am a big fan of content-specific instances. Some instances off the top of my head that fit this description:
…and I am sure there are many others. I just think that having a focus like that provides a more interesting local instance environment than a large, generalist instance, though both have a place.